Long COVID: A multi-omics based anti-inflammatory immune signature

Does Long COVID involve immune suppression rather than chronic inflammation? This article explores how multi-omics research reveals a distinct anti-inflammatory immune signature that could improve diagnosis and monitoring of Long COVID.
Long COVID inflammatory immune signature concept

Long COVID: Highlights of the Study

Anti-inflammatory signature: Patients with Long COVID Syndrome (LCS) show a consistent pattern of anti-inflammatory molecules in blood plasma.

Diagnostic potential: This proteomics and metabolomics pattern could be used for diagnostics and monitoring of Long COVID.

Possible mechanisms: Alternatively polarized macrophages may play a role in the underlying pathomechanisms of LCS.

Key molecules identified: High levels of anti-inflammatory oxylipins, including omega-3 fatty acids, were detected in LCS using eicosadomics.

New perspective: These findings suggest a new vision for understanding immune responses in COVID-19 recovery.

Reference / Contact:
Johannes J. Kovarik, Andrea Bileck, Gerhard Hagn, Mariann Gyöngyösi, Klaus G. Schmetterer, Christopher Gerner
mariann.gyongyosi@meduniwien.ac.at | klaus.schmetterer@meduniwien.ac.at | christopher.gerner@univie.ac.at

Access the full publication: Read the study
Kovarik J.J. et al. A multi-omics based anti-inflammatory immune signature in Long COVID syndrome, iScience, 2023.

Enjoyed this article?

Get the full foundation — free

Download the Immune System Fundamentals Guide and get the molecular context that makes every article on this site click into place.

Read Our Next Article

Ginseng root supporting immune function and vitality
Diet

GINSENG effects

Can Panax ginseng reduce inflammation and protect the immune system? This article explores how ginsenosides target key pathways to support health and may help prevent chronic diseases.

Falcon symbolizing strong and resilient immune system control
Diet

Master your immune system

How can you harness your immune system for better health? This article explains how lifestyle factors like diet, sleep, exercise, and supplementation help maintain balance and optimize immune function.

Scroll to Top