Why should we trust an epigenetic test like GENOWME in clinical practice? This article examines five scientific and regulatory arguments supporting its credibility—while also outlining the technical limits and clinical caveats that a careful interpretation must always include.
What if your biological age is not fixed, but continuously shaped by how you eat, move, sleep, and manage stress? This article explains how epigenetic markers translate everyday choices into measurable changes in aging, and how lifestyle can literally slow—or accelerate—your healthspan.
Your DNA Isn’t Your Destiny — Your Daily Choices Are Read More »
What if aging is less about the genes you inherit than the way your lifestyle rewrites them over time? This article explores how epigenetics transforms nutrition, sleep, stress, movement, and environment into measurable biological signals that shape your healthspan long before disease appears.
Epigenetics as a Preventive Tool for a Better Healthspan Read More »
What are the best times to eat based on your location? Calculate your personalized circadian eating window using sunrise, solar noon, and sunset data based on your geographic location.
How does the proton motive force (Δp) act as the universal electrochemical intermediate of bioenergetics, linking mitochondrial respiration to ATP production, cellular signaling, and disease? This course booklet develops a quantitative framework integrating membrane potential, pH gradients, and thermodynamic constraints.
Proton Motive Force — The Chemiosmotic Engine of Life Read More »
How can the same mitochondrial membrane potential (ΔΨm) reflect both optimal energy production and severe dysfunction? This course booklet explains how ΔΨm emerges from bioenergetic fluxes and why both its increase and collapse define distinct pathological states requiring opposite therapeutic strategies.
ΔΨm — The Two Faces of Mitochondrial Dysfunction Read More »
How does Complex I convert electron free energy into mechanical work to pump the first proton across the inner mitochondrial membrane? This course booklet develops a quantitative and mechanistic understanding of how redox energy is transduced into proton pumping at the entry point of the respiratory chain.
Complex I — From Electron Free Energy to the First Proton Pump Read More »
What if inflammation, sepsis, and cancer immune evasion all share the same thermodynamic flaw?
This article explores how a single bioenergetic switch in immune cells—between OXPHOS and glycolysis—drives disease across sepsis, rheumatoid arthritis, and lung cancer.
The M1/M2 Thermodynamic Axis: One Trade-Off Across Disease Read More »
Can damaged mitochondria trap the brain in chronic inflammation and drive depression?
This article explores how mitochondria–lysosome crosstalk failure locks microglia into a self-sustaining inflammatory loop, and how this mechanism connects to sepsis, T cell dysfunction, and the IRG1–itaconate axis.
When Microglia Can’t Clean Up Their Mitochondria Read More »
If we can track our biomarkers, nutrition, and sleep, why do we ignore the air we breathe?
This article explores how untested air, making up 90% of our daily exposure, delivers a continuous, low-grade biological signal to every cell in their body.
The Forgotten Layer of Your Exposome: Indoor Air Quality and Its Biological Consequences Read More »
