{"id":18688,"date":"2023-01-24T12:29:10","date_gmt":"2023-01-24T12:29:10","guid":{"rendered":"https:\/\/drpascalmensah.com\/?p=18688"},"modified":"2026-04-17T09:45:30","modified_gmt":"2026-04-17T09:45:30","slug":"covid-long","status":"publish","type":"post","link":"https:\/\/drpascalmensah.com\/fr\/covid-long\/","title":{"rendered":"COVID long\u202f: une signature immunitaire anti-inflammatoire bas\u00e9e sur une approche multi-omique"},"content":{"rendered":"\t\t
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Points cl\u00e9s de l\u2019\u00e9tude<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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Signature anti-inflammatoire <\/strong>: Les patients atteints de COVID long (LCS) pr\u00e9sentent un sch\u00e9ma coh\u00e9rent de mol\u00e9cules anti-inflammatoires dans le plasma sanguin.<\/p>

Potentiel diagnostique<\/strong> : Ce profil en prot\u00e9omique et m\u00e9tabolomique pourrait \u00eatre utilis\u00e9 pour le diagnostic et le suivi du COVID long.<\/p>

M\u00e9canismes possibles <\/strong>: Des macrophages alternativement polaris\u00e9s pourraient \u00eatre impliqu\u00e9s dans les m\u00e9canismes sous-jacents du syndrome.<\/p>

Mol\u00e9cules cl\u00e9s identifi\u00e9es<\/strong> : Des niveaux \u00e9lev\u00e9s d\u2019oxylipines anti-inflammatoires, y compris des acides gras om\u00e9ga-3, ont \u00e9t\u00e9 d\u00e9tect\u00e9s chez les patients atteints de LCS gr\u00e2ce \u00e0 l\u2019eicosadomique.<\/p>

Nouvelle perspective<\/strong> : Ces r\u00e9sultats sugg\u00e8rent une nouvelle vision pour comprendre les r\u00e9ponses immunitaires apr\u00e8s le COVID-19.<\/p>

R\u00e9f\u00e9rence \/ Contact<\/strong> :
Johannes J. Kovarik, Andrea Bileck, Gerhard Hagn, Mariann Gy\u00f6ngy\u00f6si, Klaus G. Schmetterer, Christopher Gerner
mariann.gyongyosi@meduniwien.ac.at | klaus.schmetterer@meduniwien.ac.at | christopher.gerner@univie.ac.at<\/p>

Acc\u00e9der \u00e0 la publication compl\u00e8te<\/strong> : lire l\u2019\u00e9tude<\/em><\/span><\/a>
Kovarik J.J. et al. A multi-omics based anti-inflammatory immune signature in Long COVID syndrome<\/em>, iScience, 2023.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Le COVID long implique-t-il une suppression immunitaire plut\u00f4t qu\u2019une inflammation chronique\u202f? Cet article explore comment la recherche multi-omique r\u00e9v\u00e8le une signature immunitaire anti-inflammatoire sp\u00e9cifique, pouvant am\u00e9liorer le diagnostic et le suivi des patients. <\/p>\n","protected":false},"author":1,"featured_media":18196,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[133],"tags":[161,226,220],"class_list":["post-18688","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-covid","tag-immunite","tag-immunologie","tag-metabolism"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/drpascalmensah.com\/fr\/wp-json\/wp\/v2\/posts\/18688","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/drpascalmensah.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/drpascalmensah.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/drpascalmensah.com\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/drpascalmensah.com\/fr\/wp-json\/wp\/v2\/comments?post=18688"}],"version-history":[{"count":1,"href":"https:\/\/drpascalmensah.com\/fr\/wp-json\/wp\/v2\/posts\/18688\/revisions"}],"predecessor-version":[{"id":21415,"href":"https:\/\/drpascalmensah.com\/fr\/wp-json\/wp\/v2\/posts\/18688\/revisions\/21415"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/drpascalmensah.com\/fr\/wp-json\/wp\/v2\/media\/18196"}],"wp:attachment":[{"href":"https:\/\/drpascalmensah.com\/fr\/wp-json\/wp\/v2\/media?parent=18688"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/drpascalmensah.com\/fr\/wp-json\/wp\/v2\/categories?post=18688"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/drpascalmensah.com\/fr\/wp-json\/wp\/v2\/tags?post=18688"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}